Genetic Testing of Embryos (PGT)

Preimplantation Genetic Testing is a type of IVF treatment where assessment of the genetic material within the embryos is performed prior to them being transferred. This allows accurate embryo selection and is hence, most likely to result in a healthy, successful pregnancy. The 2 types of testing include PGT-A and PGT-M.

Preimplantation Genetic Testing for Aneuploides (PGT-A)

Preimplantation Genetic Testing for Aneuploidies, PGT-A (formerly PGS) is a genetic test performed on embryos to identify numerical chromosomal abnormalities (aneuploidy).

One would need to undergo ovarian stimulation to retrieve eggs from the ovaries. These are then used to create embryos with the help of sperm. Five days later, embryos that reach the blastocyst stage are biopsied and cryopreserved. The genetic material is then sent for testing to a specialised laboratory. It can take 3-4 weeks to get the results. A chromosomally normal embryo is then transferred into the womb in a subsequent cycle.

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Why use PGT-A?

- Increases pregnancy rates per transfer due to the selection of a normal embryo.

- Reduction in miscarriage rate as the vast majority are due to aneuploidy.

- Increase in the likelihood of having a healthy baby as some pregnancies with chromosomal anomalies can give rise to the birth of baby with a serious illness.

- Reduction in time and cost to achieve a pregnancy.

- Reduces risk of multiple pregnancy by a encouraging the transfer of a single embryo.

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Who should use PGT-A?

- PGT-A is particularly important for patients over 35, as aneuploidy rate increases with maternal age from approximately 50% at maternal age under 35, to approximately 80%, at age 42.

- Those with a history of recurrent miscarriages and implantation failures.

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What are the limitations of PGT - A?

- Accuracy is ~98%, hence prenatal testing is recommended.

- PGT-A tests only the samples produced by embryo biopsy, not whole embryos.

- PGT-A does not detect structural abnormalities that do not involve gains or losses of genetic material.

PGT-A | Preimplantation Genetic Testing-Aneuploidy | Embryo Biopsy (3:10)

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Genetic Testing of Embryos for Aneuploidies (PGT-A) - £6,449.00

This includes the following

- HFEA Fee

- Nurse Consultation

- Cycle Management 

- Ultrasound Monitoring

- Egg Collection under sedation

- Sperm Preparation

- Genetic Testing and Embryo freezing  of upto 3 embryos

- Embryo Storage for 1 year

- Consultation with Nutritionist or Counsellor*

* First cycle of treatment


Additional charges as applicable

- Genetic Testing and Embryo Freezing £449 (per additional embryo)

- ICSI £1,199

- IMSI £559

- Blastocyst culture £699

- Blood Tests £249



Preimplantation Genetic Testing for Monogenic disorders (PGT-M)

Preimplantation Genetic Testing for Monogenic disorders, PGT-M (formerly PGD) is an early genetic diagnostic test for embryos produced during IVF, prior to their transfer to the uterus.

Like PGT-A treatment, one would need to undergo ovarian stimulation to retrieve eggs from the ovaries to create embryos with the help of sperm. Embryo biopsy is performed at the blastocyst stage and the embryos are cryopreserved. The genetic material is then sent for testing to a specialised laboratory. It can take 3-4 weeks to get the results. An embryo that is free of disease is then transferred into the womb in a subsequent cycle.

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Who should perform PGT-M test?

PGT-M is indicated for couples with personal or familial high-risk for single gene conditions including Cystic Fibrosis, Fragile-X syndrome,Muscular dystrophy, Huntington’s disease, and others.

PGT-M | Preimplantation Genetic Testing - Monosomy | Embryo Biopsy (3:00)

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Genetic Testing of Embryos for Monogenic Disorders (PGT-M) - £10,049

This includes the following

- HFEA Fee

- Nurse Consultation

- Cycle Management

- Ultrasound Monitoring

- Egg Collection under Sedation

- Sperm Preparation

- Genetic Testing and Embryo Freezing of up to 9 embryos

- Embryo Storage for 1 year

- Consultation with Nutritionist or Counsellor*

*1st cycle of treatment

Additional charges as applicable

- Genetic testing and Embryo Freezing £349 (per additional embryo)

- ICSI £1199

- IMSI £559

- Blastocyst culture £699

- Blood Tests £249

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