Recurrent Miscarriage

A miscarriage is a pregnancy loss at some point in the first 23 weeks of gestation. When this happens three or more times it is called recurrent miscarriage. Around one woman in every 100 has recurrent miscarriage.

Recurrent Miscarriage Management

In situations of recurrent miscarriage additional tests are recommended for both the female and the male partners. These include chromosome analysis, thrombophilia screening, 3D saline scan or hysteroscopy, immune tests, thyroid function tests and blood sugar levels for the female partner. Whereas the male partners undergo chromosome analysis and sperm DNA fragmentation tests.

Women who have supportive care from the beginning of a pregnancy have a better chance of a successful birth. Treatment depends on the problem identified and may include blood thinners, immune modulators or medication to control thyroid and blood sugar levels. Uterine anomalies such as a septum will require surgery.

Men with high DNA Fragmentation should consider lifestyle changes along with Intracytoplasmic Sperm Injection (ICSI) treatment and Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) treatment.

If a chromosomal problem is identified then embryo selection with Preimplantation Genetic Diagnosis (PGD) treatment is the treatment of choice.

And finally, there is strong evidence to suggest that embryo testing using Preimplantation Genetic Testing - Aneuploidy (PGT - A) will allow embryo selection based on chromosomal content and is likely to result in a positive outcome.

Recurrent Miscarriage Management (2:58)

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