Understanding Miscarriage & Pregnancy Loss

Understanding Miscarriage & Pregnancy Loss

Pregnancy loss is an emotionally devastating experience for any expecting parent. Unfortunately, miscarriage is not as rare as many might believe, with around 10-20% of known pregnancies ending in miscarriage. 

While a single miscarriage is distressing, experiencing recurrent miscarriages adds another layer of grief, frustration, and confusion for those trying to conceive. 

In this article, we will discuss miscarriage, the causes of recurrent miscarriage, and the various tests and treatments available. We'll also highlight the importance of seeking a Recurrent Miscarriage Specialist and the potential use of IVF for recurrent miscarriage.


What is Miscarriage?

A miscarriage is defined as the spontaneous loss of a pregnancy before the 20th week. 

Most miscarriages occur within the first trimester, often before the woman even realizes she is pregnant. While miscarriages are common, the emotional toll they take on expecting parents is significant. Feelings of sadness, guilt, and frustration can linger long after the physical symptoms have passed.


What is Recurrent Miscarriage?

Recurrent miscarriage, also known as recurrent pregnancy loss (RPL), is defined as having two or more consecutive pregnancy losses before the 20th week of gestation. This affects about 1% of couples trying to conceive and may be caused by various factors. These may include genetic issues, hormonal imbalances, structural problems in the uterus, immune system disorders, or lifestyle factors. The emotional and psychological impact of recurrent miscarriage is profound, leaving parents in search of answers and treatment options.


Causes of Recurrent Miscarriage

Recurrent miscarriage may be due to a wide range of factors. Understanding the potential causes is crucial to determining the right Recurrent Miscarriage Test and treatment. Some of the common causes include:


Genetic Factors

Chromosomal abnormalities in the embryo are the most common cause of early miscarriage. In many cases, the embryo may not develop properly, leading to a miscarriage. A Recurrent Miscarriage Test involving genetic screening can help identify if either parent is carrying a genetic abnormality that could contribute to pregnancy loss.


Hormonal Imbalances

Hormonal issues such as luteal phase defect, thyroid imbalances, or polycystic ovary syndrome (PCOS) can interfere with a pregnancy’s development, leading to miscarriage. Blood tests to assess hormone levels are part of the Recurrent Miscarriage Test suite.


Uterine Abnormalities

Physical abnormalities of the uterus, such as a septate uterus, fibroids, or scarring (Asherman’s syndrome), can interfere with implantation or the growth of a fetus. Ultrasounds, hysteroscopies, and other imaging tests are often recommended to examine the structure of the uterus.


Blood Clotting Disorders

Conditions like antiphospholipid syndrome (APS) or thrombophilia can cause blood clots to form in the placenta, leading to pregnancy loss. A Recurrent Miscarriage Test for blood clotting disorders may include testing for antibodies and coagulation factors.


Immune System Issues

Sometimes, a woman’s immune system may mistakenly attack the developing fetus, leading to a miscarriage. Immunological testing can determine if autoimmune conditions, such as lupus, are causing recurrent miscarriages.


Lifestyle Factors

Factors such as smoking, excessive alcohol consumption, and uncontrolled medical conditions like diabetes can increase the risk of recurrent miscarriage. Lifestyle modifications may reduce the likelihood of further pregnancy loss.


Tests for Recurrent Miscarriage

If you've experienced two or more consecutive miscarriages, it’s important to undergo a comprehensive Recurrent Miscarriage Test to identify the underlying cause. The following are some of the tests typically recommended:


Genetic Testing

Genetic testing of both partners is often one of the first Recurrent Miscarriage Test steps. Karyotyping can reveal if either parent has a chromosomal abnormality that may be passed on to the embryo, causing a miscarriage.


Hormonal Testing

Blood tests to measure hormone levels, such as progesterone, thyroid hormones, and prolactin, are often part of the testing process. Hormonal imbalances can interfere with embryo implantation and early pregnancy development.


Uterine Imaging

Imaging techniques such as ultrasounds, hysterosalpingograms (HSG), or hysteroscopies allow doctors to examine the shape and condition of the uterus. These tests can detect fibroids, polyps, adhesions, or congenital abnormalities that may be causing miscarriages.


Blood Clotting and Immune System Testing

Blood tests for antiphospholipid antibodies, lupus anti-coagulant, and other clotting factors help determine if an autoimmune condition or blood clotting disorder is responsible for recurrent pregnancy loss.


Sperm Analysis

While recurrent miscarriage is often attributed to the woman, the man’s sperm quality can also be a contributing factor. A Recurrent Miscarriage Test may include a detailed analysis of the partner’s sperm to detect abnormalities.


Treatment Options for Recurrent Miscarriage

Once the underlying cause of recurrent miscarriage has been identified, treatment can be tailored to the specific issue. A Recurrent Miscarriage Specialist will guide you through the treatment options, which may include:

  1. Genetic Counseling and IVF with Preimplantation Genetic Testing (PGT)
    For couples with genetic issues, IVF for recurrent miscarriage combined with preimplantation genetic testing (PGT) may be recommended. During IVF, embryos are created in the lab, and PGT is used to screen the embryos for genetic abnormalities before implantation, significantly reducing the risk of miscarriage due to chromosomal issues.

  2. Hormonal Treatment
    If hormonal imbalances are identified, treatments such as progesterone supplements or thyroid medication can help regulate hormones and support a healthy pregnancy.

  3. Surgical Correction
    If a uterine abnormality like a septate uterus or fibroids is detected, surgery may be recommended to correct the issue, making it easier to carry a pregnancy to term.

  4. Anticoagulant Therapy
    For women diagnosed with antiphospholipid syndrome or other blood clotting disorders, anticoagulant medications such as low-dose aspirin or heparin may be prescribed to reduce the risk of miscarriage.

  5. Lifestyle Changes
    If lifestyle factors like smoking, obesity, or unmanaged medical conditions are contributing to miscarriages, a Recurrent Miscarriage Specialist will recommend appropriate lifestyle modifications to improve the chances of a successful pregnancy.

IVF for Recurrent Miscarriage: A Promising Option

IVF for recurrent miscarriage is becoming a more common recommendation for couples facing pregnancy loss. For those with genetic issues or unexplained recurrent miscarriage, IVF with PGT offers a way to increase the likelihood of a successful pregnancy. By selecting healthy embryos for transfer, the risk of miscarriage is reduced, allowing couples to avoid the heartache of multiple pregnancy losses.

Furthermore, IVF allows close monitoring of the pregnancy from its earliest stages, and the ability to control factors such as hormonal support and embryo quality provides an added layer of reassurance for those who have experienced recurrent miscarriages.


When to See a Recurrent Miscarriage Specialist

If you’ve experienced two or more consecutive miscarriages, it’s time to consult a Recurrent Miscarriage Specialist, such as our own Dr Irfana Koita here at IVF Matters. A specialist with the experience of knowledge of Dr Koita, will offer a comprehensive evaluation, including the necessary Recurrent Miscarriage Test series, to identify the root cause and guide you through the treatment options that are right for you. Early intervention and specialist support can significantly increase the chances of a successful pregnancy.


Finding a Miscarriage Specialist Clinic in London

For couples experiencing recurrent miscarriage, finding a trusted miscarriage specialist clinic in London is an essential step toward achieving a healthy pregnancy. London is home to several world-renowned fertility specialists offering cutting-edge diagnostics and treatments for recurrent miscarriage. IVF Matters, led by renowned Fertility Consultant, Dr Irfana Koita is one such clinic that specialise in reproductive endocrinology and fertility and provide a comprehensive approach to identifying the causes of recurrent pregnancy loss.

IVF Matters clinics in London offer advanced diagnostic tests, including the latest genetic screening technologies and immune system evaluations, as part of our Recurrent Miscarriage Test suite. We also provide tailored treatment plans, including IVF with PGT, hormonal therapy, and immunotherapy for immune-related pregnancy loss.

Moreover, IVF Matters emphasize emotional and psychological support, recognising that the journey to parenthood can be emotionally taxing, especially after multiple losses. Counseling, support groups, and holistic therapies can often be integrated into our treatment plans, providing a well-rounded approach to healing for couples, both physically and emotionally.


Conclusion: Hope After Recurrent Miscarriage

Experiencing recurrent miscarriage is emotionally and physically draining, but it's important to remember that many couples eventually go on to have successful pregnancies with the right support and treatment. 

Advances in fertility medicine, including comprehensive Recurrent Miscarriage Test options and fully-supportive treatments like IVF for recurrent miscarriage, provide new hope for those struggling with pregnancy loss.

A Recurrent Miscarriage Specialist can help guide you through this difficult journey, offering tailored care that addresses the specific challenges you face. If you're searching for answers and solutions, consulting a trusted miscarriage specialist clinic in London, such as IVF Matters, under the care of Dr Koita, can bring you closer to achieving a healthy pregnancy and fulfilling your dream of parenthood.

By taking proactive steps, undergoing the necessary tests, and following through with a customised treatment plan, you can move forward with confidence and optimism toward a future where miscarriage no longer holds you back from experiencing the joys of parenthood.


Book a FREE Advisory Call with our Recurrent Miscarriage Expert, Dr Irfana Koita. 


Schedule a Fertility Consultation with Dr Koita to discuss Recurrent Miscarriage, Miscarriage Tests and Diagnosis and potential treatment pathways.